Multiple symmetric lipomatosis (MSL)
lymph nodes not seen in CT) // differential diagnoses. liposarcoma, Cushing syndrome Growth of symmetric non-encapsulated masses of adipose tissue mostly around the face and neck, typically: rapid (!) early development, followed by slow progressive growth of adipose deposits in and around the face, neck, occipital region,supraclavicular fossa, + shoulder areas (!) |
Complete surgery necessary even if not malignant: A: Over time, - neck muscles may become compressed, reduced neck mobility (already started!) - reducing the size of the trachea and esophagus (!!) - with associated respiratory obstruction (!!) - and obstructive sleep apnea! (started, I think) - Patients also often have (later!) polyneuropathy!! (90%!) Malignant transformation into liposarcoma has been reported in very rare cases. → https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=2398&lng=EN 2nd cause: Rare, but possible after only topical corticosteroids: "Systemic Side-Effects of Topical Corticosteroids" |
B: People with multiple symmetric lipomatosis may also develop:[4][1][5] - Peripheral neuropathy (!!) - Neurological disturbances including difficulty swallowing, hoarseness (!!) - sleep problems, - tachycardia (rapid heart rate), - fluctuation in blood pressure, and breathing issues
- Other
metabolic abnormalities or diseases such as → https://rarediseases.info.nih.gov/diseases/6957/multiple-symmetric-lipomatosis clobetasol proprionate + betamethasone for several months! (non-healing wounds etc.). kidney - HPA axis, Cushing Syndrome ...?! |
h.a.
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